欢迎来到韩大力课题组

近期发表文章:

1. Tongnian Gu#, Siqi Zhao#, Yishuang Pia, Weizhong Chena, Chuanyuan Chenb,c, Qian Liud, Min Lid, Dali Han *, and Quanjiang Ji* .Highly Efficient Base Editing in Staphylococcus aureus Using an Engineered CRISPR RNA-guided Cytidine Deaminase. Chemical Science (2018 Accepted, DIO: 10.1039/C8SC00637G. http://pubs.rsc.org/en/Content/ArticleLanding/2018/SC/C8SC00637G#! divAbstract)


2.Xin Tian#, Baofa Sun#, Chuanyuan Chen#, Chunchun Gao#, Ji Zhang#, Xingyu Lu#, Linchen Wang, Xiangnan Li, Yurong Xing, Ruijuan Liu, Xiao Han, Zheng Qi, Xiaojian Zhang, Chuan He, Dali Han*, Yun-Gui Yang*, Quancheng Kan*. Circulating tumor DNA 5-hydroxymethylcytosine as a novel diagnostic biomarker for esophageal cancer. Cell Research. (2018 Accepted, DIO: 10.1038/s41422-018-0014x,  https://www.ncbi.nlm.nih.gov/pubmed/?term=29467383)

3. Qing Dai* ∙ Sharon Moshitch-Moshkovitz* ∙ Dali Han* ∙ Nitzan Kol ∙ Ninette Amariglio ∙ Gideon Rechavi ∙ Dan Dominissini ∙ Chuan He. Nm-seq maps 2'-O-methylation sites in human mRNA with base precision. Nature Methods. 2017, doi:10.1038/nmeth.4294  

4. Dali Han* ∙ Xingyu Lu* ∙ Alan H. Shih* ∙ Ji Nie ∙ Qiancheng You ∙ Meng Michelle Xu ∙ Ari M. Melnick ∙ Ross L. Levine ∙ Chuan He.A highly sensitive and robust method for genome-wide 5hmC profiling of rare cell populations. Molecular Cell. 2016, 63, 711–719  

5.  Bo Xia* ∙ Dali Han* ∙ Xingyu Lu* ∙ Zhaozhu Sun ∙ Ankun Zhou ∙ Qiangzong Yin ∙ Hu Zeng∙ Menghao Liu ∙ Xiang Jiang ∙ Wei Xie ∙ Chuan He ∙ Chengqi Yi. Bisulfite-free, Base-resolution analysis of 5-formylcytosine at the genome scale. Nature Methods 2015, 12, 1047-1050 

 6. Xingyu Lu*∙ Dali Han* ∙ Zhao Boxuan Simen* ∙ ChunXiao Song ∙ LiSheng Zhang ∙ Louis C Doré ∙ Chuan He. Base-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics. Cell Research 2015, 25, 386-389 

Beijing Insitute of Genomics