Beijing Insitute of Genomics
1. Novel nucleic acid modification sequencing technology:
Development of new high-throughput sequencing
technologies to epigenetically identify newly identified
genes.Factors to carry out functional studies,
interpretation of DNA modifications (5hmC, 5fC, etc.)
And RNA modification (m6A, 2'OMe, etc.) on the regulation of gene expression.
2. Tumor epigenetics
To study the apparent appearance of tumor cells and
immune cells in the tumor microenvironment
Genetic modification dynamic changes, clarify the
mechanism of tumor immune escape.
3. Machine learning and artificial intelligence algorithm development
Integrate epigenome, epigenome data and clinical medical information to accurately predict, diagnose and treat cancer and disease and achieve wisdom medical treatment.